Scale-Up and Optimization in Preparative Chromatography: Principles and Biopharmaceutical Applications (Chromatographic Science)
Ajoy Velayudhan
Presenting guidelines for predicting and improving separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; data comparisons from all stages of production; and industrial separation schemes for products such as synthetic molecules, antibody fragments, IgG, growth factors, and plasmid DNA. The book covers external constraints, separation economics, correlations for transport and kinetic phenomena, and the configuration and parameters of column design.
Kategorien:
Jahr:
2002
Auflage:
1
Verlag:
CRC Press
Sprache:
english
Seiten:
346
ISBN 10:
0824708261
ISBN 13:
9780824708269
Datei:
PDF, 3.10 MB
IPFS:
,
english, 2002
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